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KMID : 0359920080270050611
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Korean Journal of Nephrology
2008 Volume.27 No. 5 p.611 ~ p.615
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A Case of Interstitial Pneumonitis Associated with Sirolimus Treatment in Renal Transplantation Recipient
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Lee Ji-Young
Byun Seung-Woon
Yeo Young-Sun
Kim Soon-Bae
Chang Jai-Won
Yang Won-Seok
Park Jung-Sik
Park Su-Kil
Kim Sun-Young
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Abstract
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Sirolimus is a promising immunosuppressive drug for renal transplantation to avoid nephrotoxicity of calcineurin inhibitor. However, it has been associated with uncommon but, important pulmonary toxicity. We present a case of sirolimus related dyspnea with abnormal chest radiographic finding in a 63 year old male renal transplantation recipient. There was no evidence of bacterial, fungal, or viral infection. Dose reduction of sirolimus resulted in a significant improvement of the symptoms and chest radiographic finding.
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KEYWORD
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Sirolimus, Kidney Transplantation, Pneumonitis, Adverse effects
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